Ai wishes to become a real woman after suspecting her sister is involved with the doctor, while Ryuji Hirasaka plans perverted experiments targeting Hikaru. The doctor steps in to save Hikaru and Ai, using a novel invention that causes the sisters to engage with each other while Ai believes it is all part of a dream. This first episode of the Night Shift Nurses Kranke series runs for 28 minutes in 3D animation with completely uncensored futanari scenes. The storyline sets up the bizarre medical trials that follow the characters through their serialized adventures.